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Magic Mushroom Liquid Cultures

A liquid culture is a 20 ml syringe of living Psilocybe cubensis mycelium in a sterile nutrient solution. Unlike spores, it does not have to germinate first, and because each culture comes from one selected line, the genetics are more uniform. We keep 21 cubensis cultures, from Golden Teacher and B+ to Penis Envy and Jack Frost, each with a needle and disinfectant wipes.

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Every culture in this category is Psilocybe cubensis. For truffle-forming species, see our magic truffle liquid cultures; for the full overview of formats, see liquid culture syringes.

What do you get with a liquid culture?

  • A 20 ml syringe of active mycelium in a sterile nutrient solution
  • A sterile needle, packed separately
  • Disinfectant wipes

The mycelium is alive when it arrives, so treat it like fresh produce: in the fridge from the moment you unpack it.

Liquid culture or spore syringe?

Liquid cultureSpore syringe
ContentsLiving myceliumDormant spores
First visible growthFaster, no germination stepSlower, spores germinate first
GeneticsOne selected line, more uniformEvery spore slightly different
Shelf life in the fridgeUp to 2 to 3 monthsLonger

Liquid culture suits people who want a predictable start. Spores are the choice for microscopy and for people who are interested in genetic variation. The full explanation is in our liquid culture syringe guide and in liquid culture vs spore syringe.

Which strains are available?

Background on each strain is in the magic mushroom strain library. The azurescens culture is a different species from cubensis, with its own needs.

How should you store a liquid culture?

  • In the fridge at 2 to 8 °C, never in the freezer
  • Away from light and heat
  • Use within 2 to 3 months; fresher culture is more active
  • Let the syringe reach room temperature and shake it gently before use

Our liquid culture syringe manual describes handling in more detail. If a syringe looks unusually cloudy or smells off, do not use it; the troubleshooting center tells you what to check.

Our liquid cultures are sold for microscopy and educational purposes. Rules on fungal cultures differ per country, so check what applies where you live before ordering.

Questions about liquid cultures

A liquid culture holds living mycelium that grows straight away; a spore syringe holds dormant spores that have to germinate first. Liquid culture genetics are more uniform.

Up to 2 to 3 months in the fridge at 2 to 8 °C. Do not freeze it.

A sterile needle and disinfectant wipes.

Yes, seven truffle-forming strains such as Mexicana, Tampanensis and Galindoi. They are in magic truffle liquid cultures.

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